Synthesized very-long-chain polyunsaturated fatty acids improves retinal function in mice
February 8th 2021Paul S. Bernstein, MD, PhD, leads a team of University of Utah investigators that has developed a method for synthesizing large enough quantities of very-long-chain polyunsaturated fatty acids to evaluate their potential sight-preserving properties.
Phase I study of polyhexanide seeks safety, tolerability characteristics for patients with AK
February 1st 2021The study focused the safety and tolerability of increasing doses of polihexanide eye drops in order to choose a dose that would be tested in a phase III clinical trial in patients with acanthamoeba keratitis.
A rift in the retina may help repair the optic nerve
January 28th 2021Investigators at the Wilmer Eye Institute at the Johns Hopkins University School of Medicine conducting experiments in mouse tissues and human cells found that they may be able improve the success rate for regrowing nerve cells damaged by blinding diseases.
Neurophth and AAVnerGene partner on AAV capsids for next-gen ophthalmic gene therapy
January 19th 2021Neurophth Therapeutics, Inc (Neurophth) and AAVnerGene Inc have announced the launch of a strategic partnership that will grant Neurophth global rights to mutually select adeno-associated virus (AAV) capsids for the creation of the next-generation ophthalmic gene therapy.
Enrollment completed for first Phase 3 study of perfluorohexyloctane
January 19th 2021Bausch + Lomb has enrolled 599 participants in the first of two Phase 3 studies evaluating perfluorohexyloctane as a first-in-class investigational drug to treat the signs and symptoms of dry eye disease associated with meibomian gland dysfunction.