News

Cambridge, England?Research published in the January issue of the British Journal of Ophthalmology found not only a strong association between pack years of cigarette smoking and age-related macular degeneration (AMD) but also an increased risk of AMD in nonsmokers exposed to passive smoking.

Montr?al?A modified version of the Amsler grid, with a backlit screen and other changes, improves detection of scotomas and is easier for patients and clinicians to use, according to designer Elie Khouri, MD, a Montr?al ophthalmologist.

Bethesda, MD?The Age-Related Eye Disease Study (AREDS) indicatedthat supplementation with micronutrients has a protective effect inpreventing the development of advanced stages of age-relatedmacular degeneration (AMD). Emily Y. Chew, MD, reviewed thefindings of the role of micronutrients for the treatment of AMD.

Boston?Ruboxistaurin mesylate (Arxxant, Eli Lilly), an investigational drug that is an oral protein kinase C (PKC) beta inhibitor, reduced the occurrence of sustained moderate vision loss by 40% in patients with moderately severe to very severe nonproliferative diabetic retinopathy, reported Lloyd P. Aiello, MD, PhD.

Boston?The 12-month results of two randomized clinical trials of ranibizumab (Lucentis, Genentech) indicate that the drug shows encouraging signs of activity against vascular endothelial growth factor (VEGF) in age-related macular degeneration (AMD).

Cleveland?Anti-vascular endothelial growth factor (VEGF) therapy has been validated as the foundation treatment for age-related macular degeneration (AMD), stated Lawrence J. Singerman, MD, who provided an update on pegaptanib sodium (Macugen, OSI Pharmaceuticals/Eyetech Pharmaceuticals).

Miami?Optical coherence tomography (OCT) can be a valuable tool for evaluating the status of choroidal neovascularization (CNV) in patients with wet age-related macular degeneration (AMD), particularly when new drugs are being used to treat the disease, said Philip J. Rosenfeld, MD, PhD, associate professor of ophthalmology, Bascom Palmer Eye Institute, Miami.

New York?Anecortave acetate (Retaane 15 mg suspension, Alcon Laboratories) seems to be safe and effective for the treatment of exudative age-related macular degeneration (AMD) compared with photodynamic therapy (PDT) with verteporfin for injection (Visudyne, Novartis Ophthal-mics/QLT Inc.).

Frankfurt, Germany?Twenty-three gauge vitrectomy instrumentation has become available and offers surgeons an alternative to 25-gauge instruments. Claus Eckardt, MD, looked at the pros and cons of these smaller instruments.

Durham, NC?The Retisert implant (Bausch & Lomb), a nonbiogradable device containing fluocinolone acetonide, is approved for the treatment of posterior uveitis and seems promising in the treatment of diabetic macular edema (DME) and vein occlusion in clinical trials, according to Glenn Jaffe, MD.

Royal Oak, MI?Vitrectomy should be considered for some eyes withdiffuse diabetic macular edema (DME). The procedure seems to be along-term efficacious treatment in some eyes, according to Tarek S.Hassan, MD.

Winter Haven, FL?A number of new pharmacologic options for exudative age-related macular degeneration (AMD), mostly designed to block different steps in the angiogenic cascade, are in various stages of development and testing, and some may one day be shown to improve outcomes, said Michael J. Tolentino, MD, director of clinical research, Center for Retina and Macular Disease, Winter Haven, FL.

Kyoto, Japan?Seasonal variation in IOP is important to take into account when evaluating those patients with glaucoma and particularly those with steroid-induced ocular hypertension, according to Kazuhiko Mori, MD, PhD.

Minneapolis?Refractive surgeons should incorporate rather than dismiss corneal refractive therapy (orthokeratology) and contact lens fitting because those techniques can have a synergistic benefit rather than play a competitive role in a refractive surgery practice, according to David R. Hardten, MD.

Oklahoma City, OK?A state bill requiring children entering kindergarten, first, and third grades to receive vision screenings has passed the Senate and is being considered in the House.

Mentor, OH?To meet the needs of a growing global customer base, Volk Optical has appointed Tim Warrell to the newly created position of marketing and customer service manager.

Irvine, CA?3D Vision Systems Inc., a digital imaging technology developer, has added industry veteran John Gilbert to its medical advisory board.

Washington?New York State's Department of Health will include new questions about visual impairment and access to eyecare in its annual 2006 Behavioral Risk Factor Surveillance System program.

Be honest. Has this ever happened to you? You are about to get out of the shower in the morning and suddenly ask yourself the question: "Did I shampoo my hair?" And you're not sure of the answer?

Portland, OR?Mass vision screening of school-age children was first recommended in 1983. At that time there was not a large population of children of preschool age, a situation that has changed markedly since then because today many more 3- and 4-year-olds are in a preschool setting. However, there is still no standardization in vision screening.

Dorado, Puerto Rico?Torsional phacoemulsification offers cataract surgeons a new way to remove nucleus material more efficiently and safely than traditional longitudinal ultrasound, reported Richard J. Mackool, MD, who spoke during the Current Concepts in Ophthalmology meeting here.

Madison, WI - Uniform testing and reporting criteria are needed toidentify amblyogenic risk factors in children and prevent thedevelopment of amblyopia. Leslie W. France, CO, described theevidence base for the guidelines to detect amblyogenic riskfactors.

During resident clinic recently, I met an elderly woman suffering from age-related macular degeneration (AMD). Upset with 20/300 vision in her left eye, she was desperate to maintain her right eye's 20/25 vision.

Calgary, Alberta, Canada?In a single-surgeon study of glaucoma patients with uncontrolled IOP on maximally tolerated medical therapy, argon laser trabeculoplasty (ALT) was associated with a greater IOP-lowering effect than selective laser trabeculoplasty (SLT), reported Bryce Ford, MD.

Baltimore?The problem of an increasingly large population of patients with diabetes has spawned a novel and sometimes controversial approach to management: consultation via telemedicine assessment. Ingrid Zimmer-Galler, MD, discussed this high-tech approach to care at the recent Current Concepts in Ophthalmology meeting.