Researchers expand preclinical safety and pharmacokinetics studies with anti-VEGF agents
September 15th 2008An animal study evaluating the safety of intravitreal antiVEGF agents found no evidence of retinal toxicity with repeat dosing based on electroretinography and histologic evaluation. Retinal penetration and pharmacokinetics were also investigated.
Understanding corneal hysteresis fundamental in grasping biomechanics concepts
September 15th 2008Daniel S. Durrie, MD, explains corneal hysteresis as measured with the Ocular Response Analyzer (ORA, Reichert) and why he believes further research with the ORA may enhance understanding of corneal biomechanics.
Studies still weighing supplements for tear dysfunction
September 15th 2008Supplementation with omega-3 fatty acids, omega-6 fatty acids, and fish oils in patients with dry eye probably will decrease the overall inflammatory state of the eye based on subjective evidence, but objective placebo-controlled trials should be conducted to validate this recommendation.
IOL cutter small size, strength boons to IOL explantation procedure
September 15th 2008A proprietary IOL cutter (Packer/Chang IOL Cutter, Microsurgical Technology) is a micro-scissors that can be inserted through a paracentesis incision while the surgeon holds the optic with a forceps through the phacoemulsification incision. The instrument facilitates safe removal of IOLs.
Changes to surgical routine cut risk of postoperative endophthalmitis
September 15th 2008A cluster of cases of postoperative endophthalmitis at the Prince Charles Eye Unit, King Edward Hospital, Windsor, England, over a 4-month period led to a thorough investigation of etiologic factors and multiple changes in the perioperative routines.
Analysis: Choosing between growth and death?
September 15th 2008There is an inherent tension between the appeal of maintaining a successful, secure business and the desire to expand the business. According to Dr. McDonnell it is much more common for practices and departments to wait too long before beginning the process of adding excellent people to build upon a successful and vibrant operation.
Iridex lasers receive FDA clearance
September 15th 2008Iridex Corp. has received 510(k) clearance from the FDA for a family of laser systems (IQ 532, IQ 577, IQ 630-670, and IQ 810) and their associated delivery devices to deliver laser energy in three different modes (CW-Pulse, MicroPulse, and LongPulse).
Day 3 Audio Coverage of the ESCRS 2008 Congress
September 15th 2008In today's podcast, Nick Mamalis, MD, talks about preoperative and postoperative endophthalmitis prevention. Also, Okihiro Nishi, MD, discusses the Ridley Medal Lecture he delivered about a new IOL refilling procedure to restore accommodation. Additionally, Walter Sekundo, MD, talks about femtosecond lenticule extraction, and Luis Antonio Ruiz, MD, relays outcomes of a recent study regarding intrastromal correction of presbyopia.
Tiolat Oy announces new name and expansion plans
September 15th 2008On August 20th, Tiolat Oy, manufacturer of the iCare Tonometer, underwent a makeover and changed its name to iCare Finland Oy. In a conversation with Ophthalmology Times Europe, newly-appointed CEO Ari Tiukkanen outlined the reasons behind the recent name change, and discussed how the new name fits into the company's plans for the future.
Bimanual vs coaxial MICS: who wins?
September 15th 2008Bimanual microincision cataract surgery (MICS) and microaxial phacolemulsification provide optically better incisions but bimanual MICS respects more corneal prolateness than microaxial phaco, Mr Jorge Alio, told delegates. "MICS is associated with less corneal oedema in the short term and less inducation of corneal aberrations in the long term," he said.
Lens refilling brings accommodation two steps closer
September 15th 2008Ophthalmology is perhaps two steps closer to a possible clinical application of lens refilling with silicon gel for restoring ocular accommodation thanks to a refined procedure developed by Dr Okihiro Nishi, MD of the Nishi Eye Hospital, Japan.
FLEx: just as effective but cheaper than Femto-LASIK
September 15th 2008Refractive outcomes for Femtosecond Lenticule Extraction (FLEx) are getting close to those of eximer-based Femto-LASIK, and patients are expressing high degrees of satisfaction with both techniques, Dr Walter Sekundo told delegates at a session on current trends in laser refractive surgery.