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For healthy eyes undergoing sub-Bowman's keratomileusis using advanced technology, outcomes for efficacy and safety, including effects on dry eye, are similarly excellent using either an 8- or 9-mm diameter flap.

Enhanced low-compliance tubing on a proprietary phaco platform may help to increase vacuum limit safely and allow the surgeon to lower the bottle height or decrease the incision size with greater stability and safety without reduced ergonomic convenience.

Dr. McDonnell recalls a scenario involving hotel key cards and corporate sponsorship at a recent AAO meeting.

A 1-year extension of a two-year phase II study of treatment of diabetic macular edema allowed ranibizumab dosing frequency to increase from every 2 or 3 months to monthly.

The preoperative condition of the ocular surface affects outcomes after implantation of IOLs in patients undergoing cataract surgery.

Topcon Medical Laser Systems Inc. has launched a system upgrade for its family of lasers offering scanning technology and tissue-sparing sub-threshold treatment options.

Results of a prospective, randomized pilot study suggest that a topical nonsteroidal anti-inflammatory drug, bromfenac 0.09%, may be a useful addition to an anti-vascular endothelial growth factor agent, intravitreal ranibizumab, in patients being treated for exudative age-related macular degeneration.

The UV + riboflavin crosslinking procedure triggers the development of mild stromal haze in rabbit corneas, but it is not because of myofibroblast generation,a s it is for late haze after PRK.

Microincisional vitrectomy surgery using 23- and 25+-gauge instrumentation enhances the surgical management of complex macular pathologies.

A number of procedures are available to address presbyopia, each with its advantages and disadvantages.

Careful investigation using a systematic approach to troubleshoot patients dissatisfied after multifocal IOL implantation usually can identify an underlying cause that can be effectively managed with conservative intervention and avoidance of further intraocular surgery.

Julia A. Haller, MD, details the complex medical case of a blind African teeneager recently freed from slavery in the Sudan.

A triple-function 23-gauge laser endoscope is available for video, imaging, and laser during an array of retinal procedures.

A new aspheric treatment for presbyopia, P-curve, considers both the total Q value and the corneal asphericity among other parameters to induce the negative spherical aberration that is lost with aging.

Results of a prospective, double-masked, randomized study indicate that combination treatment with the dexamethasone implant 0.7 mg and laser photocoagulation is very well tolerated in patients with DDME and provides better functional and anatomic outcomes than laser treatment alone.

Intracameral injection of perfluoropropane gas in a non-expansile concentration (14%) appears to hasten resolution of corneal edema in eyes with acute corneal hydrops.

An ultra-small cataract incision size might not be optimal to maintain wound integrity.

Two studies of a fusion protein (VEGF Trap-Eye, Regeneron) showed that all doses of the drug, including those administered every 2 months, to treat neovascular age-related macular degeneration were noninferior to ranibizumab (Lucentis, Genentech) in the number of patients who maintained their visual acuity

The MERITAGE Study (NeoVista), a study to evaluate the effect of epimacular brachytherapy in patients with exudative age-related macular degeneration previously treated with ranibizumab (Lucentis, Genentech), showed that the treatment results of radiation therapy were “interesting and encouraging” at the 2-year time point, according to Pravin Dugel, MD.

The HORIZON Study for retinal vein occlusion, an extension study composed of patients treated in the BRAVO Study for branch retinal vein occlusion and the CRUISE study for central retinal vein occlusion, showed that 0.5-mg intravitreal injections of ranibizumab (Lucentis, Genentech) inhibit vascular endothelial growth factor as in previous studies of the efficacy of the drug.

A head-to-head comparison of ranibizumab (Lucentis, Genentech) and bevacizumab (Avastin, Genentech) in the Comparison of Age-related Macular Degeneration Treatments Trials indicated that at the 1-year time point, both drugs were clinically equivalent for treating the disease, said Daniel Martin, MD

Placido corneal topography is established technology for corneal imaging, but whether it is the best diagnostic technique to detect forme fruste keratoconus when screening refractive surgery candidates is a matter of debate.

Results of a preclinical pilot study demonstrate ocular iontophoresis accelerates transfer of topically applied riboflavin into the cornea compared with conventional application, said George O. Waring IV, MD.

Results from a prospective clinical trial show that corneal collagen crosslinking is a promising modality for treatment of keratoconus and postLASIK ectasia, said Peter S. Hersh, MD.

Leading refractive surgeons agree wavefront-guided ablation is a significant advance in laser vision correction, but have different opinions about its role in treating myopic eyes with low higher-order aberrations.

Omega-3 fatty acid supplementation results in substantially faster healing when used as an adjunctive therapy before and after PRK. The cornea re-epithelialized faster, the vision recovered faster, and the tear break-up time improved in patients randomly assigned to omega-3 fatty acid supplementation, according to Nikki Heidi Ong, MD.

A newly developed proprietary injector system allows implantation of the investigational fluid-filled accommodating IOL through a small incision.

The mature, brunescent nucleus is a challenge for all phaco surgeons.

Patients with severe or progressive zonulopathy are at risk for late postoperative subluxation or dislocation of a capsular tension ring-IOL-capsular bag complex, which occurred about 6 years after implantation.

Results from 2 years of follow-up in a study of presbyopia correction with femtosecond laser intrastromal correction show continued safety, refractive stability, and maintenance of improvements in near visual acuity.