FDA approves trial plan and fast tracks Ascidian Therapeutics' ACDN-01 in Stargardt Disease
January 29th 2024ACDN-01 is the first-ever RNA exon editor to enter clinical development and the only clinical-stage therapeutic targeting the genetic cause of Stargardt disease. Ascidian expects to initiate enrollment in Phase 1/2 STELLAR study in the first half of 2024.
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President and CEO of Ashvattha Therapeutics talks about the company's unique nanomedicine technology
January 28th 2024David Hutton of Ophthalmology Times talks with Jeffrey Cleland, PhD, President and CEO of Ashvattha Therapeutics, about the company's D-4517.2, a unique nanomedicine technology for the treatment of wet AMD and DME.
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Coherus to divest ophthalmology franchise to Sandoz for $170 Million
January 23rd 2024According to the companies, the deal also includes Coherus’ CIMERLI biologics license application, ophthalmology sales and select field reimbursement teams. Coherus will now focus on its oncology business.
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Iuvo BioScience acquires Promedica International
January 21st 2024The combined organization will support all aspects of ophthalmic clinical research, from front of the eye to back of the eye, leveraging an even larger team of experts with centuries of collective experience in ophthalmology.
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According to the company, ABBV-RGX-314 continues to be well tolerated in over 100 patients from three dose levels with no drug-related serious adverse events. The new data was presented at the Hawaiian Eye and Retina meeting in Maui, by John Pitcher, MD, and includes 6-month results from two additional dose level 3 cohorts.
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Eyenovia re-acquires development, commercialization rights to MicroPine in US, Canada
January 16th 2024According to the company, MicroPine, currently in late phase III for pediatric progressive myopia, will complement Eyenovia’s commercial-stage asset, Mydcombi, as well as its pre-PDUFA candidate, APP13007.
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Hawaiian Eye and Retina 2024: Toric IOL pearls for correcting lower levels of astigmatism
January 15th 2024David Hutton of Ophthalmology Times talks with William Trattler, MD, about his presentation "Toric IOL pearls for Correcting Lower Levels of Astigmatism" at this year's Hawaiian Eye and Retina 2024 Meeting.
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Jane C. Edmond, MD, starts term as 2024 president of AAO
January 13th 2024According to an American Academy of Ophthalmology news release, Edmond’s priorities during her term include addressing physician and staff shortages and protecting patient safety at a time when nonphysicians are trying to expand their scope of practice into eye surgery.
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Kashani leading Optical Coherence Tomography Angiography Initiative in several multicenter studies
January 12th 2024Studies aim to develop a clinically useful biomarker of retinal capillary changes to monitor the development of a prevalent form of systemic vascular disease and cerebrovascular disease.
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Alcon’s dry eye candidate achieves positive topline results in Phase 3 trials
January 11th 2024AR-15512, a topical transient receptor potential melastatin 8 agonist, is a first-in-class product candidate for the treatment of the signs and symptoms of dry eye disease. Alcon plans to file a New Drug Application for AR-15512 with the FDA in mid-2024.
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