Banner - Collaborative Care Symposium

News
Media
Conferences
Events
Publications
CME
Partners
Subscribe
Resources

Opinion|Videos|November 29, 2024

Safety of Advanced Therapies in Clinical Trials vs Real World Experience

Author(s)Lisa J. Faia, MD , David R. Lally, MD, Scott D. Walter, MD, MSc, FASRS

Key Takeaways

Lisa J. Faia, MD asks the panel about their concerns regarding the safety of newer agents for the broad array of retinal vascular diseases, highlighting the similarities and differences between clinical trial outcomes and real-world results.

Episodes in this series

4 experts are featured in this series.

EP. 1 Case 1: Treatment-Naïve Neovascular Age-Related Macular Degeneration

4 experts are featured in this series.

EP. 2 First Line Treatment Decisions for Age-Related Macular Degeneration

4 experts are featured in this series.

EP. 3 Case 2: Diabetic Macular Edema With Severe Vision Loss

4 experts are featured in this series.

EP. 4 MOA and Improved Outcomes: Gaps in Measuring Real-World Results

4 experts are featured in this series.

EP. 5 Case 3: Persistently Active Central Retinal Vein Occlusion

4 experts are featured in this series.

EP. 6 Safety of Advanced Therapies in Clinical Trials vs Real World Experience

4 experts are featured in this series.

EP. 7 Case 4: Neovascular Age-Related Macular Degeneration with Serious Pigment Epithelial Detachment

4 experts are featured in this series.

EP. 8 Final Thoughts on Case Presentations and Advanced Therapies

Newsletter

Don’t miss out—get Ophthalmology Times updates on the latest clinical advancements and expert interviews, straight to your inbox.

Related Content

(Image credit: Ophthalmology Times) NeuroOp Guru: Understanding optic disc cupping after optic neuritis

NeuroOp Guru: Understanding optic disc cupping after optic neuritis

ByAndrew G. Lee, MD,Andrew Carey, MD

February 5th 2026

(Image credit: NYU Grossman School of Medicine) The Residency Report: PreserFlo microshunt vs trabeculectomy—five-year trial insights

The Residency Report: PreserFlo microshunt vs trabeculectomy—five-year trial insights

ByPreeya Mehta, MD,Jonathan S. Williams, MD,Louis R. Pasquale, MD

February 2nd 2026

(Image credit: AdobeStock/NickArt) From awareness to action: Optimizing ocular surface health in glaucoma

From awareness to action: Optimizing ocular surface health in glaucoma

ByElisabeth M. Messmer, MD, FEBO

January 31st 2026

MacTel Decoded: Rethinking Conventional Approaches with Novel Neuroprotective Strategies

January 30th 2026

When Mites Meet Their Match: Empowering Patients With Targeted Treatment for Demodex Blepharitis

January 30th 2026

Latest CME

EnVision Summit

In-Person Event

EnVision Summit

February 13-16, 2026

(COPE Credit) Time Matters in GA: The Impact of Early Detection and Proactive Treatment Approaches

(COPE Credit) Time Matters in GA: The Impact of Early Detection and Proactive Treatment Approaches

Laxmi V. Devisetty, MD; Rodney P. Coe, MD, MS; Majda Hadziahmetovic, MD; Xiao Yi (Ellie) Zhou, MD

(CME Track) Expanding Horizons in Toric IOLs: Translating Technological Advances Into Improved Patient Outcomes

(CME Track) Expanding Horizons in Toric IOLs: Translating Technological Advances Into Improved Patient Outcomes

Rahul Tonk, MD, MBA

(CME Track) The TED Perspective: A Multidisciplinary Approach to Thyroid Eye Care

(CME Track) The TED Perspective: A Multidisciplinary Approach to Thyroid Eye Care

Sara T. Wester, MD, FACS; Cecelia Koetting, OD; Sophie Liao, MD; Jennifer Murdock, MD

$(CME Track) The Neural Frontier: Mapping Neurostimulation Across the DED Patient Spectrum for Refractive Surgery$

(CME Track) The Neural Frontier: Mapping Neurostimulation Across the DED Patient Spectrum for Refractive Surgery

Zeba A. Syed, MD

(CME Track) Visionary Approaches: Rethinking Therapeutic and Interventional Glaucoma Management

(CME Track) Visionary Approaches: Rethinking Therapeutic and Interventional Glaucoma Management

Rachel Simpson, MD; James Murphy, MD; Mary Qiu, MD; Jessica Steen, OD, FAAO

(COPE Track) Expanding Horizons in Toric IOLs: Translating Technological Advances Into Improved Patient Outcomes

(COPE Track) Expanding Horizons in Toric IOLs: Translating Technological Advances Into Improved Patient Outcomes

Rahul Tonk, MD, MBA

(COPE Track) The TED Perspective: A Multidisciplinary Approach to Thyroid Eye Care

(COPE Track) The TED Perspective: A Multidisciplinary Approach to Thyroid Eye Care

Sara T. Wester, MD, FACS; Cecelia Koetting, OD; Sophie Liao, MD; Jennifer Murdock, MD

(COPE Track) Patient-Centered Treatment Strategies in the Management of nAMD and DME

(COPE Track) Patient-Centered Treatment Strategies in the Management of nAMD and DME

Adrienne W. Scott, MD, FASRS; Justine Cheng, MD; Hong-Uyen Hua, MD; Sherrol A. Reynolds OD, FAAO, FNAP

$(COPE Track) The Neural Frontier: Mapping Neurostimulation Across the DED Patient Spectrum for Refractive Surgery$

(COPE Track) The Neural Frontier: Mapping Neurostimulation Across the DED Patient Spectrum for Refractive Surgery

Zeba A. Syed, MD

(COPE Track) Visionary Approaches: Rethinking Therapeutic and Interventional Glaucoma Management

(COPE Track) Visionary Approaches: Rethinking Therapeutic and Interventional Glaucoma Management

Rachel Simpson, MD; James Murphy, MD; Mary Qiu, MD; Jessica Steen, OD, FAAO

Practical Approaches to Modern Dry Eye Treatment and Management

Practical Approaches to Modern Dry Eye Treatment and Management

Marc R. Bloomenstein, OD, FAAO; Cory J. Lappin, OD, MS, FAAO; Selina R. McGee, OD, FAAO

(CME Credit) Time Matters in GA: The Impact of Early Detection and Proactive Treatment Approaches

(CME Credit) Time Matters in GA: The Impact of Early Detection and Proactive Treatment Approaches

Laxmi V. Devisetty, MD; Rodney P. Coe, MD, MS; Majda Hadziahmetovic, MD; Xiao Yi (Ellie) Zhou, MD

(CME Track) Revolutionizing nAMD and DME Management: Collaborative Strategies in the Age of Durable Treatments

(CME Track) Revolutionizing nAMD and DME Management: Collaborative Strategies in the Age of Durable Treatments

David S. Liao, MD, PhD; Chang Sup Lee, MD; Douglas Matsunaga, MD; Daniel Su, MD

(CME Track) Patient-Centered Treatment Strategies in the Management of nAMD and DME

(CME Track) Patient-Centered Treatment Strategies in the Management of nAMD and DME

Adrienne W. Scott, MD, FASRS; Justine Cheng, MD; Hong-Uyen Hua, MD; Sherrol A. Reynolds OD, FAAO, FNAP

(COPE Track) Revolutionizing nAMD and DME Management: Collaborative Strategies in the Age of Durable Treatments

(COPE Track) Revolutionizing nAMD and DME Management: Collaborative Strategies in the Age of Durable Treatments

David S. Liao, MD, PhD; Chang Sup Lee, MD; Douglas Matsunaga, MD; Daniel Su, MD

(CME Track) Clinical Consultations™: Framing a New Approach to Geographic Atrophy Management – Expert Insights into Recent Developments

(CME Track) Clinical Consultations™: Framing a New Approach to Geographic Atrophy Management – Expert Insights into Recent Developments

Yasha Modi, MD; Carolyn Majcher, OD, FAAO, FORS

(COPE Track) Clinical Consultations™: Framing a New Approach to Geographic Atrophy Management – Expert Insights into Recent Developments

(COPE Track) Clinical Consultations™: Framing a New Approach to Geographic Atrophy Management – Expert Insights into Recent Developments

Yasha Modi, MD; Carolyn Majcher, OD, FAAO, FORS

(COPE Track) Rapid Reviews in Retina™: Emerging Updates from Winter 2025 – Addressing the Wealth of New Data in Treatments for nAMD and DME

(COPE Track) Rapid Reviews in Retina™: Emerging Updates from Winter 2025 – Addressing the Wealth of New Data in Treatments for nAMD and DME

David M. Brown, MD, FACS; Dilraj S. Grewal, MD

(CME Track) Rapid Reviews in Retina™: Emerging Updates from Winter 2025 – Addressing the Wealth of New Data in Treatments for nAMD and DME

(CME Track) Rapid Reviews in Retina™: Emerging Updates from Winter 2025 – Addressing the Wealth of New Data in Treatments for nAMD and DME

David M. Brown, MD, FACS; Dilraj S. Grewal, MD

Living With X-Linked Retinitis Pigmentosa: What We Can Learn From a Patient’s Experience

Living With X-Linked Retinitis Pigmentosa: What We Can Learn From a Patient’s Experience

Lejla Vajzovic, MD, FASRS; Ramiro Maldonado, MD

Living With X-Linked Retinitis Pigmentosa: What We Can Learn From a Patient’s Experience

Living With X-Linked Retinitis Pigmentosa: What We Can Learn From a Patient’s Experience

Lejla Vajzovic, MD, FASRS; Ramiro Maldonado, MD

(CME Track) Collaborative Community Connections™: Mastering the Management of nAMD and DME Through Therapeutic Innovation

(CME Track) Collaborative Community Connections™: Mastering the Management of nAMD and DME Through Therapeutic Innovation

Veeral Sheth, MD, MBA, FASRS, FACS; Mark R. Barakat, MD, FASRS; Geeta Lalwani, MD; Xiao Yi Zhou, MD

(COPE Track) Collaborative Community Connections™: Mastering the Management of nAMD and DME Through Therapeutic Innovation

(COPE Track) Collaborative Community Connections™: Mastering the Management of nAMD and DME Through Therapeutic Innovation

Veeral Sheth, MD, MBA, FASRS, FACS; Mark R. Barakat, MD, FASRS; Geeta Lalwani, MD; Xiao Yi Zhou, MD

Navigating the Glaucoma Therapeutic and Surgical Landscape: From Conventional to Cutting-Edge

Navigating the Glaucoma Therapeutic and Surgical Landscape: From Conventional to Cutting-Edge

Deborah Ristvedt, DO; Melissa Tawa, OD, FAAO

(COPE Track) Neurotrophic Keratitis: Multidisciplinary Approaches to Enhance Patient Outcomes

(COPE Track) Neurotrophic Keratitis: Multidisciplinary Approaches to Enhance Patient Outcomes

Melissa Barnett, OD, FAAO, FSLS, FBCLA; Cecelia Koetting, OD, FAAO, DipABO; Quan Đông Nguyễn, MD, MSc; Jennifer Li, MD

(CME Track) Neurotrophic Keratitis: Multidisciplinary Approaches to Enhance Patient Outcomes

(CME Track) Neurotrophic Keratitis: Multidisciplinary Approaches to Enhance Patient Outcomes

Melissa Barnett, OD, FAAO, FSLS, FBCLA; Cecelia Koetting, OD, FAAO, DipABO; Quan Đông Nguyễn, MD, MSc; Jennifer Li, MD

(CME Track) The Neural Network: Exploring The Role of Neuromodulation in Dry Eye Disease Management

(CME Track) The Neural Network: Exploring The Role of Neuromodulation in Dry Eye Disease Management

Marjan Farid, MD; John Hovanesian, MD; Beeran Meghpara, MD

(COPE Track) The Neural Network: Exploring The Role of Neuromodulation in Dry Eye Disease Management

(COPE Track) The Neural Network: Exploring The Role of Neuromodulation in Dry Eye Disease Management

Marjan Farid, MD; John Hovanesian, MD; Beeran Meghpara, MD

(CME Track) Clinical Case Connections: Expert Insights on Applying Therapeutic Innovations in nAMD

(CME Track) Clinical Case Connections: Expert Insights on Applying Therapeutic Innovations in nAMD

Nathan C. Steinle, MD

(CME Track) Toric IOLs Unleashed: From Technological Progress to Patient Success

(CME Track) Toric IOLs Unleashed: From Technological Progress to Patient Success

Tanner Ferguson, MD; Taj Nasser, MD, FWCRS

(CME Track) Clinical Case Connections: Understanding the Impact of Advances in Treatment for DME and DR

(CME Track) Clinical Case Connections: Understanding the Impact of Advances in Treatment for DME and DR

David A. Eichenbaum, MD

(COPE Track) Clinical Case Connections: Understanding the Impact of Advances in Treatment for DME and DR

(COPE Track) Clinical Case Connections: Understanding the Impact of Advances in Treatment for DME and DR

David A. Eichenbaum, MD

(COPE Track) Clinical Case Connections: Expert Insights on Applying Therapeutic Innovations in nAMD

(COPE Track) Clinical Case Connections: Expert Insights on Applying Therapeutic Innovations in nAMD

Nathan C. Steinle, MD

(COPE Track) Toric IOLs Unleashed: From Technological Progress to Patient Success

(COPE Track) Toric IOLs Unleashed: From Technological Progress to Patient Success

Tanner Ferguson, MD; Taj Nasser, MD, FWCRS

(CME Credit) Navigating Pharmacological Presbyopia Treatment for Enhanced Patient Care

(CME Credit) Navigating Pharmacological Presbyopia Treatment for Enhanced Patient Care

Jacob Lang, OD, FAAO; Selina R. McGee, OD, FAAO; Neda Shamie, MD

(COPE Credit) Navigating Pharmacological Presbyopia Treatment for Enhanced Patient Care

(COPE Credit) Navigating Pharmacological Presbyopia Treatment for Enhanced Patient Care

Jacob Lang, OD, FAAO; Selina R. McGee, OD, FAAO; Neda Shamie, MD

Neurotrophic Keratitis Insights: An Interactive Corneal Sensitivity Testing Workshop

Neurotrophic Keratitis Insights: An Interactive Corneal Sensitivity Testing Workshop

John D. Gelles, OD, FAAO, FIAOMC, FCLSA, FSLS, FBCLA; John Hovanesian, MD, FACS

(COPE Track) Small Mites, Big Impact: Revolutionizing Demodex Blepharitis Care

(COPE Track) Small Mites, Big Impact: Revolutionizing Demodex Blepharitis Care

Arjan Hura, MD; Neda Shamie, MD; Kristin Barnes, OD

(CME Track) Small Mites, Big Impact: Revolutionizing Demodex Blepharitis Care

(CME Track) Small Mites, Big Impact: Revolutionizing Demodex Blepharitis Care

Arjan Hura, MD; Neda Shamie, MD; Kristin Barnes, OD

Rapid Reviews in Retina™: Emerging Updates from Spring 2025—Addressing the Wealth of New Data in Treatments for Neovascular Retinal Disease

Rapid Reviews in Retina™: Emerging Updates from Spring 2025—Addressing the Wealth of New Data in Treatments for Neovascular Retinal Disease

SriniVas Sadda, MD, FARVO; Nathan Steinle, MD

Interventional Dry Eye: A Stepwise Treatment & Management Approach

Interventional Dry Eye: A Stepwise Treatment & Management Approach

Mark Schaeffer, OD, FAAO; Mile Brujic, OD, FAAO; Nate Lighthizer, OD, FAAO, FAAOMS; Selina R. McGee, OD, FAAO

Trending on Ophthalmology Times - Clinical Insights for Eye Specialists

Metformin use associated with reduced incidence of intermediate AMD

MeiraGTx Licenses complement-targeted geographic atrophy program from ZipBio

Looking back at the 2025 EnVision Summit

Last year in glaucoma at EnVision Summit 2025

China's NMPA approves ZEISS ARTEVO 750 and ARTEVO 850 ophthalmic surgical microscopes for clinical use