Ruboxistaurin results: Eli Lilly plans more trials
February 1st 2003Indianapolis-Eli Lilly and Co. will delay the submission of its ruboxistaurin for the treatment of diabetic retinopathy and diabetic macular edema (DME) after two clinical trials failed to achieve satisfactory results on disease progression.
International partners: InSite Vision, SIFI take OcuGene test to Italy
February 1st 2003Alameda, CA-InSite Vision Inc. and SIFI (Societa Industria Farmaceutica Italiana), a leading Italian pharmaceutical company, will exclusively manufacture, distribute, and promote the OcuGene genetic glaucoma test in Italy.
Fixed drug combination might offer better trough control
January 15th 2003Orlando-A carefully designed comparison study has shown that the fixed combination of dorzolamide-timolol (Cosopt, Merck) is at least as effective as its concomitant components and might provide better trough control in some patients, said Stanley J. Berke, MD, FACS.
Iris color changes less in eyes treated with unoprostone
January 15th 2003Orlando-The incidence of iris hyperpigmentation associated with unoprostone isopropyl ophthalmic solution 0.15% (Rescula, Novartis) was about 1% in two long-term studies, a rate that compares favorably with the incidence of 10% to 20% associated with latanoprost ophthalmic solution (Xalatan, Pharma-cia) in similar patient populations, reported Bernard E. McCarey, PhD.
IOP-lowering efficacy of bimatoprost, latanoprost weighed
January 15th 2003Bimatoprost 0.03% (Lumigan, Allergan) offers more efficacy than latanoprost 0.005% (Xalatan, Pharmacia) for lowering elevated IOP and is similarly well tolerated, according to the results of a 6-month, multicenter, randomized, double-masked study.
Diurnal studies show benefits of prostaglandin analogues
January 15th 2003Orlando-Although challenging to set up and conduct, studies that check glaucoma patients' IOP at intervals around the clock for 24 hours or longer provide valuable data about the ability of a medication to lower IOP and reduce fluctuation.
SLP holds promise for detection of glaucomatous change
January 15th 2003Orlando-In scanning laser polarimetry (SLP), eye-specific correction of corneal polarization axis and magnitude can be obtained for the quantitative assessmentof the peripapillary retinal nerve fiber lay-er (RNFL) if macular-based strategies are used in eyes free of macular pathology, according to glau-coma specialist David S. Greenfield, MD.
Improved form of brimonidine has fewer contraindications
January 15th 2003Brimonidine tartrate 0.15% (Alphagan P, Allergan) is a "new and improved" version of brimonidine 0.2% (Alphagan, Allergan). It continues to have an efficacy profile similar to the one ophthalmologists have grown used to with brimonidine 0.2%.
Severity of dry eye linked to ablation depth, not flap size
January 15th 2003Fullerton, CA-An analysis of tear film function after LASIK and LASEK indicates patients fared equally in the two groups when LASEK was performed for high myopia.Tear film dysfunction seems to be best correlated to the depth of the ablation and not flap dimension, according to Robert Lingua, MD.
Controlled trial: Topical serum application an effective therapy for bleb oozing
January 15th 2003Orlando-Topical application of autologous serum 20% is effective for fortifying the bleb wall and stopping aqueous oozing, but cessation of the oozing may be associated with an increase in IOP, reported Atsuo Tomidokoro, MD, PhD.
Dual function laser system is big boon to anterior segment surgeons
January 15th 2003The Selecta Duet (Lumenis), a new dual-purpose laser system, brings anterior segment surgeons a cost-effective and space-saving solution for treating both glaucoma patients undergoing selective laser trabeculoplasty (SLT) and pseudophakic patients in need of Nd:YAG laser capsulotomy for secondary cataract.
Ophthalmology Times, Nominated for Two Jesse H. Neal Awards for Editorial Excellence
January 2nd 2003Ophthalmology Times, a leading publication of Advanstar Healthcare Communications, announced today that it has been nominated for two awards in the 49th annual Jesse H. Neal National Business Journalism Awards competition.Ophthalmology Times is a finalist in the following categories: Best Single Issue of Newspaper/News Tabloid for the October 15, 2002 issue, and Best Regularly Featured Department or Column for the new InDispensable section. Neal Award winners will be revealed at the awards luncheon in New York City on March 12th.