Nextech and Ocuco partner to deliver seamless end-to-end eyecare platform
The partnership will integrate Ocuco’s optical software solution, Acuitas 3, with Nextech’s Ophthalmic Platform.
Study finds geographic and institutional disparities for DR and DME clinical trials
Results showed an unequal distributions of these clinical trials among rural and low-income populations.
Vantage Biosciences doses first patient in phase 2 study of VX-01, oral therapy for nonproliferative diabetic retinopathy
VX01-DR-201, is a phase 2, multicenter, double-masked, randomized, placebo-controlled study in patients with moderate to severe NPDR without center-involved diabetic macular edema (CI-DME).
Oculis completes enrollment in Phase 3 DIAMOND-1 and DIAMOND-2 trials for DME eye drop candidate
Topline data from both Phase 3 trials is expected in the second quarter of 2026, with NDA submission to follow thereafter.
Pykus Therapeutics completes enrollment in trial evaluating PYK-2101
PYK-2101 is a focal hydrogel retinal sealant for use in patients undergoing surgery for a detached retina.
Harrow expands VEVYE Access for All program to Klarity-C patients
Under the Vevye Access for All program, patients with a Klarity-C prescription can switch to Vevye for $59 per bottle.
Opthea to lay off approximately 65% of company
The announcement follows the decision to discontinue the COAST and ShORe trials in wet age-related macular degeneration after the COAST trial failed to meet its primary end point.
Presbyopia treatment success begins with patient-centered care
Personalizing treatment options and setting realistic expectations are crucial.
Updated guidelines enhance choriocapillaris imaging in AMD with SS-OCTA
Compensation techniques in swept-source optical coherence tomography angiography improve accuracy by correcting signal loss from drusen and other artifacts
Novel multistage model enhances OCT GA segmentation
Researchers introduce a multistage dual-branch network to improve accuracy and efficiency
EMA application filed by Bayer to expand aflibercept 8 mg indication to include retinal vein occlusion
In the European Union and United Kingdom, aflibercept 8 mg (Eylea HD in the US) is currently approved for neovascular age-related macular degeneration and diabetic macular edema
Relationship between fasting C-peptide and diabetic retinopathy in patients with type 2 diabetes mellitus
Below a specific threshold, FCP exerts a protective effect, but above that threshold the protective effect becomes uncertain.
FDA accepts biologics license application from Outlook Therapeutics for ONS-5010 for the treatment of wet AMD
A Prescription Drug User Fee Act (PDUFA) goal date of August 27, 2025, was set by the organization.
Opus Genetics reports 1-month pediatric results in gene therapy for inherited retinal disease
The new data builds upon previously reported 6- and 12-month positive results from adult patients treated in the same study.
Tenpoint Therapeutics submits NDA application to FDA for BRIMOCHOL PF for the treatment of presbyopia
BRIMOCHOL PF’s combination of brimonidine and carbachol produces a “pinhole effect,” which is intended to improve depth of focus and sharpen near and distant impact.
Breaking barriers: Australian Society of Ophthalmologists’ first woman CEO steps up
Katrina Ronne shares her vision to empower ophthalmologists, champion equity, and strengthen advocacy for better eye health outcomes across Australia.
Large language model-generated summaries improve interdisciplinary communication in ophthalmology
Although it improved interdisciplinary communication, ongoing review and safety monitoring are necessary for successful clinical implementation.
Early-onset atopic dermatitis linked to higher risk of pediatric uveitis
A study found that children with early-onset atopic dermatitis have a higher risk of developing uveitis and should be closely monitored for its onset.
Alumis and Acelyrin file a definitive proxy statement for proposed merger
Each company will hold a respective special meeting of stockholders to vote on the approval of the merger.
Nordic Pharma receives CE Mark for canalicular gel Lacrifill
Nordic Pharma plans to announce commercialization details in the near future for the dry eye disease treatment
Santen receives marketing authorization application approval from NMPA of China for tafluprost/timolol maleate (Tapcom) in patients with open-angle glaucoma
Tapcom is a preservative-free, fixed-combination eye drop of tafluprost 0.0015% and timolol 0.5% for lowering intraocular pressure.
Part 6: Biggest innovations in ophthalmology in 50 years
In celebration of Ophthalmology Times' 50th anniversary, we asked leading experts in the field what they see as the biggest innovation in ophthalmology in the past 5 decades.
Orasis Pharmaceuticals’ prescription pilocarpine hydrochloride ophthalmic solution 0.4% (Qlosi) for presbyopia available in the US
The novel corrective eye drop can be prescribed through pharmacy partners BlinkRx or Medvantx
Analysis of an AI system for improved detection of diabetic retinopathy
Researchers from the Czech Republic found that an AI system showed higher sensitivity and specificity for screening diabetic retinopathy compared to telemedicine evaluations.
Part 5: Biggest innovations in ophthalmology in 50 years
In celebration of Ophthalmology Times 50th anniversary, we asked leading experts in the field what they see as the biggest innovation in ophthalmology in the last 5 decades.
A case of retinal detachment in tertiary syphilis
Tertiary syphilis, which can develop years to decades after the initial infection, is characterized by chronic inflammatory damage affecting multiple organ systems.
Part 4: Biggest innovations in ophthalmology in 50 years
Doctors warn TikTok & Instagram reels may be damaging eyes long-term
Recent estimates show that there are over 2 billion users on Instagram, of which over 726.8 million interact with reels on the platform.
Novel radiosurgical platform to treat a case of uveal melanoma
Uveal melanoma, which primarily affects Caucasian patients, is the most common primary intraocular tumor in adults2 that most often affects the choroid (90%), ciliary body (6%), and iris (4%)
Avisi Technologies releases 6-month interim results from VITA trial
The trial is designed to assess the safety and effectiveness of Avisi Technologies' investigational VisiPlate device in patients with open-angle glaucoma.