Epinastine exhibits tolerability, efficacy in case study scenario
February 15th 2010The multimodal anti-allergy agent epinastine hydrochloride 0.05% (Elestat, Inspire Pharmaceuticals) is an ideal treatment option for the management of seasonal allergic conjunctivitis and is a particularly good choice in patients who have dry eye disease as a comorbidity, according to Laurie D. Barber, MD
Anti-VEGF for AMD a top advancement
February 3rd 2010Anti-vascular endothelial growth factor (VEGF) treatments for neovascular age-related macular degeneration represent the most significant advance in ophthalmology over the past decade, according to 52% of respondents to an online survey of members of the American Academy of Ophthalmology conducted in December.
Reichert restructures marketing function
February 3rd 2010Reichert Inc. has restructured its marketing function in an effort ?to meet the growing demands of the company?s vast product portfolio and improve performance through better focus and accountability,? according to Jerry C. Cirino, chairman and chief executive officer.
1-year results show ongoing benefit of ranibizumab for diabetic macular edema
February 1st 2010An updated analysis of data from an ongoing phase II study of intravitreal ranibizumab treatment for diabetic macular edema shows that functional and anatomic benefits observed at 6-month primary efficacy endpoint are generally maintained at 1 year after switching to a "prn" dosing schedule.
Radiation, injections reduce treatment burden for age-related macular degeneration
February 1st 2010A preliminary study of epimacular brachytherapy showed that radiation and antivascular endothelial growth factor injections reduced the treatment burden in patients with neovascular age-related macular degeneration.
Implant is new approach to uveitis
February 1st 2010A single sustained-release dexamethasone intravitreal implant resulted in resolution of inflammation and improvement in visual acuity (VA) in patients with intermediate or posterior uveitis through 26 weeks in a multicenter, randomized, controlled clinical trial.
Fixed-combination therapies are compared in studies
January 15th 2010Pooled results from two randomized, investigator-masked parallel group clinical trials show that the fixed combination fo brimonidine tartrate 0.2%-timolol maleate 0.5% produced greater IOP lowering than the fixed combination of dorzolamidehydrochloride 2%-timolol maleate 0.5%, whether the fixed combination products were used alone or as an adjunct to treatment with a prostaglandin analogue.
Abbott Medical Optics responds to FDA warning of cleaning validation
January 15th 2010In response to an FDA warning of cleaning validation at one of its plants, Abbott Medical Optics said problematic manufacturing processes were restricted to production of its ophthalmic viscosurgical device, 3% sodium hyaluronate, which is no longer being made or sold.