Clinical Diagnosis

Fort Lauderdale, FL-Both Heidelberg Retina Tomograph (HRT, Heidelberg Engineering) exams and stereoscopic optic disc photographs can show abnormalities that pre- dict glaucomatous visual-field abnormalities as early as 4 years before visual-field conversion occurs, according to results of an analysis conducted at the University of California San Diego, La Jolla.

Fort Lauderdale, FL-What constitutes glaucoma progression and the relationship between progressive structural and functional injury? These were the main questions researchers set out to answer during a glaucoma mini-symposium at the annual meeting of the Association for Research in Vision and Ophthalmology.

Vista, CA-John Hawley, vice president of Heidelberg Engineering, served as an expert panelist at the Life Sciences Industry Council program, "Innovations in Eye Disease Technology," in Irvine, CA.

Dayton, OH-Move over a few disc diameters from the optic nerve head to assess the retinal thickness in the para-macular region for early diagnosis and close monitoring of the glaucomatous process. That's the message of Talia Technology Inc., Tampa.

New York-Pfizer Inc. will invest $400 million to expand its New Jersey facilities and potentially add 1,300 jobs, but plans to close five research and development sites around the world-including two in the United States- and other former Pharmacia Corp. offices as it begins the difficult logistical transition of its $57 billion takeover.

Fort Lauderdale, FL-When assessing a patient with dry eye, clinicians should keep the time of day in mind, said Carolyn G. Begley, OD, MS.

Editor's Note: Anterior uveitis is the most common type of intraocular inflammation. Among patients with inflammation localized primarily to the anterior chamber, 50% or more are HLA-B27 positive. Inaddition, a number of these patients with HLA-B27-associated anterior uveitis have, or will develop, an associated systemicdisorder such as ankylosing spondylitis,reactive arthritis (formerly known asReiter's syndrome), inflammatory bowel disease, or psoriatic arthritis.

CA-The FDA approval of gatifloxacin ophthalmic solution 0.3% (Zymar, Allergan) marks a milestone as the first fourth-generation fluoroquinolone to enter the ophthalmic market. The therapy for the treatment of bacterial conjunctivitis caused by susceptible strains of bacteria also has a unique mechanism to prevent development of antibiotic resistance, according to Allergan.

Salt Lake City-Dysphotopsias, the unwant-ed optical images seen at night, pose an annoying and sometimes debilitating effect for cataract patients receiving IOLs with a truncated edge. To minimize these effects, efforts to modify the IOL edge have paid off, according to Randall J. Olson, MD.

Omaha, NE-The Ocular Hypertension Treatment Study (OHTS) clearly demonstrat-ed that topical IOP-lowering medications can delay the onset of primary open-angle glaucoma. In addition, the OHTS study also revealed two very important secondary messages, which may be as important as the primary finding, according to M. Roy Wilson, MD.

New York-The European Commission is wrapping up its investigation into a proposed merger of pharmaceutical giants Pfizer Inc. and Pharmacia Corp.

Orlando-Optic nerve head (ONH) imaging forms an essential part of the management of suspected glaucoma, as well as in patients with established glaucomatous visual field loss, according to a London glaucoma specialist.

New York-Using a doughnut and its hole in an analogy, David S. Greenfield, MD, said glaucoma specialists are now focusing on the doughnut rather than the hole-and retinal imaging advances have made this possible.

Needham, MA-Ruthanne B. Simmons, MD, who followed in her father's footsteps to make her mark in ophthalmology and laser surgery research, died Nov. 8 of breast cancer. She was 43.

Editor's Note: This is the final story in a three-part series covering a forum on "Ethnicity and Glaucoma" at Johns Hopkins University to commemorate the 20th anniversary of the Baltimore Eye Survey.

New York-Fluctuations in IOP during the day and night can be important for the diagnosis and treatment of glaucoma, according to Robert N. Weinreb, MD, who spoke during the Glaucoma 2002 meeting here.

Tucson, AZ-Topical beta-blockers have been a mainstay of ongoing treatment for glaucoma for more than 20 years, but a new study adds to the evidence that they may not be the best option for long-term control of IOP for elderly patients.

Editor's note: This is the second story in a three-part series covering a forum on "Ethnicity and Glaucoma" at Johns Hopkins University to commemorate the 20th anniversary of the Baltimore Eye Study. The meeting was sponsored by Johns Hopkins University School of Medicine and Ophthalmology Times and supported through an unrestricted educational grant from Alcon Laboratories Inc.

New York-Glaucoma therapy of 10 years ago has no application today, according to Robert D. Fechtner, MD, who opened a session on glaucoma and cataract surgery at the Glaucoma 2002 meeting here.

Los Angeles-Considering the limited availability of published randomized trials, glaucoma surgeons should remain skeptical about the safety and efficacy of viscocanalostomy and deep sclerectomy with collagen wick, said Donald S. Minckler, MD.

Dr. Kornmehl: Thank you all for participating in this discussion about conductive keratoplasty (CK). Ed, what is the mechanism of CK

Baltimore-Race, that ever-sensitive subject in American culture, was the focus of a day-long meeting, "Ethnicity & Glaucoma: The Past, Present, and Future," at Johns Hopkins' Bloomberg School of Public Health.

Fort Lauderdale, FL-Estrogen-whether endogenous or from hormone replacement therapy (HRT)-appears to help prevent cataract formation, according to Australian researcher Christine Younan, MD, who reported her findings at the annual meeting of the Association for Research in Vision and Ophthalmology.

New York-Certain glaucoma cases present a major challenge to the clinician. Participants in a session at the Glaucoma 2002 meeting here discussed some of these unusual conditions.

New York-The official definition of glaucoma has changed over the years to downplay the role of IOP, although IOP does remain a central issue in the treatment and prevention of the condition. Such was the conclusion drawn from discussions at the Glaucoma 2002 meeting here.

San Antonio, TX-Before prescribing one of the newer medications for glaucoma, clinicians should ask what drugs the patient may be taking for aches and pains-especially non-steroidal anti-inflammatory agents (NSAIDs), including something as innocuous as aspirin, said William E. Sponsel, MD.

Boston-The incidence of overcorrection following PRK and LASIK is fortunately very small, generally less than 5%. Unfortunately, the incidence of consecutive hyperopia after RK is significantly greater and, over time, becomes higher with a hyperopic shift, said Helen K. Wu, MD.

A genetically engineered molecule designed to kill cancers by destroying their rapidly growing blood vessels offers a new line of attack against age-related macular degeneration (AMD) and other retinal conditions, said Alan Garen, PhD.

Many physicians wrinkle their noses at the idea of selling products in the office. But what about offering patients educational materials at the time of diagnosis?

New Orleans-A system incorporating a narrow-beam excimer laser with an active tracking system to detect minuscule eye motions is effective in the LASIK correction of myopia and astigmatism, according to Marguerite B. McDonald, MD, clinical professor of ophthalmology at Tulane University School of Medicine here.