Article

No frown lines as onabotulinumtoxinA turns 10

April 15 marked the 10-year anniversary of FDA approval of onabotulinumtoxinA (Botox Cosmetic, Allergan) to help improve the look of moderate to severe frown lines between the eyebrows in patients aged 18 to 65 years.

Irvine, CA-April 15 marked the 10-year anniversary of FDA approval of onabotulinumtoxinA (Botox Cosmetic, Allergan) to help improve the look of moderate to severe frown lines between the eyebrows in patients aged 18 to 65 years.

OnabotulinumtoxinA was first approved by the FDA in 1989 for the treatment of strabismus and blepharospasm, making it the first botulinum toxin type A product approved in the world. Since its first approval, onabotulinumtoxinA has been recognized by regulatory authorities worldwide as an effective treatment for 25 different indications in approximately 85 countries.

Globally, about 30 million vials of onabotulinumtoxinA have been distributed, according to Allergan.

For more articles in this issue of Ophthalmology Times eReport, click here.

Newsletter

Don’t miss out—get Ophthalmology Times updates on the latest clinical advancements and expert interviews, straight to your inbox.

Related Videos
(Image credit: Ophthalmology Times) Neda Shamie_Controversies in Modern Eye Care 2025
(Image credit: Ophthalmology Times) The synergy of cornea, cataract, and refractive surgery through the decades: insights from George O. Waring IV, MD
(Image credit: Ophthalmology Times) AGS 2025: A look at Gemini and the MIGS revolution with Mona Kaleem, MD
(Image credit: Ophthalmology Times) AGS 2025: Constance Okeke, MD, highlights 1-year Streamline canaloplasty outcomes
(Image credit: Ophthalmology Times) AGS 2025: Two-year data of bio-interventional cyclodialysis with scleral allograft with Leon W. Herndon Jr, MD
(Image credit: Ophthalmology Times) AGS 2025: Aqueous humor outflow improvement after excimer laser trabeculostomy with Clemens Strohmaier, PhD
(Image credit: Ophthalmology Times) Thomas W. Samuelson, MD, shares clinical perspectives on DSLT, SLT, and glaucoma management
Image credit: Ophthalmology Times; Dean McGee Eye Institute resident Ashley Ooms, MD, explores gray area strabismus surgery complications in AUPO poster
Image credit: Ophthalmology Times; EnVision Summit 2025: Sonia H. Yoo, MD, shares what to expect from the cataract and refractive agenda
© 2025 MJH Life Sciences

All rights reserved.