News

New Orleans—Late-onset bleb leakage needs to be controlled to avoid such complications as blebitis or bleb-related endophthalmitis, which can result in poor visual outcome, reported Philip P. Chen, MD, during the glaucoma subspecialty day meeting at the American Academy of Ophthalmology annual meeting.

New Orleans—Adding a third or fourth medication to a glaucoma patient's therapeutic regimen has many drawbacks but a few potentially positive aspects as well and should be considered on an individual patient basis, said Shan C. Lin, MD, assistant professor of clinical ophthalmology, University of California, San Francisco, and San Francisco General Hospital.

New Orleans—Patients with refractory glaucoma may be candidates for transscleral or endoscopic cyclophotocoagulation (CPC) to lower IOP (Figure 1), although there is no direct evidence comparing the two approaches, explained Neeru Gupta, MD, PhD.

Barcelona, Spain—The Zyoptix system (Bausch & Lomb) for wavefront-guided ablation is as effective as the conventional Planoscan (Bausch & Lomb) LASIK procedure in the correction of low to moderate myopia. Zyoptix, however, is advantageous because it induces less total, higher-order, and third-order aberrations. In addition, the quality of vision under low illumination and with low-contrast objects is better than that achieved with Planoscan, according to Jorge Castanera, MD, and Carlos Rios, OC.

New Orleans—Wavefront-guided LASIK re-treatments in post-LASIK eyes resent a good option for refractive correction, according to results of a small study in which nearly all eyes showed a reduction of pre-existing total aberrations and some reduction in higher-order aberration components.

New Orleans—A LASIK multifocal treatment approach for presbyopia produced accurate distance vision corrections accompanied by gains in near vision, according to a small Canadian trial in which patients had been followed for 1 year postoperatively. Patients who underwent the procedure also reported high overall satisfaction, said W. Bruce Jackson, MD, FRCSC, professor and chairman, department of ophthalmology, University of Ottawa, Ontario, Canada.

Lafayette, LA—The LaFaci Surgical System (Vision Pro, LLC, Opelousas, LA) allows the LASIK surgeon to perform a number of specialized functions in the surgical field through the use of one handpiece. This capability, according to the developer of the system, Leon C. LaHaye II, MD, facilitates the entire second stage, i.e., following lifting of the flap, of the LASIK procedure.

LASEK, PRK debate continues

New Orleans—LASEK, in contrast to PRK, provides a good, stable flap, and as a result of that difference, LASEK has important advantages that include less pain, less regression, and less risk of haze, said Massimo Camellin, MD, at a refractive surgery lecture during the International Society of Refractive Surgery of the American Academy of Ophthalmology annual meeting.

New Orleans—Separate prospective comparison studies of LASIK platforms have shown that the systems evaluated produced similarly successful outcomes with relatively minor differences. According to speakers at a refractive surgery session at the American Academy of Ophthalmology meeting, these studies also represent a welcome trend toward head-to-head comparisons of the various platforms and a step toward expanding evaluation criteria.

New Orleans—The Allegretto Wave excimer laser (WaveLight Laser Technologie AG, Erlangen, Germany) received high marks from users who covered its various features during the American Academy of Ophthalmology annual meeting.

New Orleans—Incorporating higher-order aberrations (HOAs) into LASIK treatment performed with aspherically optimized profiles using the MEL80 excimer laser (Carl Zeiss Meditec) increases treatment benefit without compromising refractive accuracy, said Dan Z. Reinstein, MD, MA (Cantab), FRCSC, at the ISRS subspecialty day meeting.

New Orleans—Joshua D. Stein, MD, MS, of Manhattan Eye, Ear, and Throat Hospital (MEETH), was named the winner of the second annual Ophthalmology Times Resident Writer's Award Program. The program was presented and sponsored by Advanced Medical Optics (AMO).

Joshua D. Stein, MD, MS, received his Bachelor of Arts degree from Wesleyan University with a double major in neuroscience and behavior and psychology. He then attended the Center for the Evaluative Clinical Sciences at Dartmouth Medical School and received a Master of Science degree. From there, he went on to Jefferson Medical College and obtained his Doctor of Medicine degree. Dr. Stein is currently a chief resident in ophthalmology in the New York University School of Medicine/Manhattan Eye, Ear and Throat Hospital (MEETH) residency program, and will pursue a fellowship in glaucoma at Duke University next year. Dr. Stein is a prolific researcher and investigator, having published numerous articles in peer-reviewed journals and presented his research at many national and international meetings.

Editor's Note: Joshua D. Stein, MD, MS, of New York University School of Medicine and Manhattan Eye, Ear, and Throat Hospital (MEETH), was named the winner of the second annual Ophthalmology Times Resident Writer's Award Program—presented during the American Academy of Ophthalmology annual meeting in New Orleans. Dr. Stein's winning submission is featured here. He was nominated by Laurence T.D. Sperber, MD, the residency program director and clinical associate professor of ophthalmology at New York University School of Medicine and director of the Cornea Service at MEETH in New York.

Fort Worth, TX—Alcon Laboratories Inc. has submitted the third and final reviewable unit of its new drug application (NDA) for anecortave acetate for depot suspension (Retaane) to the FDA.

Rochester, NY—Bayer HealthCare LLC's Biological Products Division has granted Bausch & Lomb (B&L) an exclusive worldwide license to its Plasmin technology for use in developing novel therapies for ocular conditions.

Vienna, Austria—In an unprecedented event, the Association of International Glaucoma Societies (AIGS) is hosting the World Glaucoma Congress in Vienna, Austria. Organizers believe the meeting, which runs July 6 to 9, will attract about 2,000 general ophthalmologists, glaucoma specialists, and industry representatives to study a disease that is debilitating to more than 100 million people worldwide.

A natural Photographer

A waterfall may just be a waterfall for many passers-by, but in the eyes of David A. Snyder, MD, the cascading water may be an intricate part of a photograph waiting to be captured.

Boston—Ultra-high-speed spectral domain optical coherence tomography (SD-OCT) is a significant advance in noninvasiveretinal imaging that allows for rapid, comprehensive screening of large areas and three-dimensional (3-D) volume rendering of the optic nerve head and fovea, said Johannes F. de Boer, PhD.

The Accreditation Council forContinuing Medical Education (ACCME) has awarded theAmerican Academy of Ophthalmology' (AAO) CME program Accreditation with Commendation, a distinction awarded to only 8% of all accredited CME providers, and one that is seldom achieved by a medical specialty society.

New Orleans—Travoprost 0.004% (Travatan, Alcon Laboratories) lowers IOP by both increasing outflow facility and improving uveoscleral outflow, according to the results of a clinical study designed to investigate the mechanism of action of travoprost.

New Orleans—Twice-daily administration of a fixed-combination product containing brimonidine 0.2% plus timolol 0.5% (Combigan, Allergan Inc.) safely and effectively lowers IOP, according to the pooled results of two 12-month, randomized, double-masked, phase III studies.

Timolol maleate ophthalmic solution 0.5% (Istalol, ISTA Pharmaceuticals), available in a new, once-a-day formulation, is as effective as a standard 0.5% timolol maleate ophthalmic solution administered twice daily to treat elevated IOP in ocular hypertension and open-angle glaucoma.

New Orleans—Results of a prospective, randomized, double-masked study demonstrate a fixed combination of travoprost 0.004% and timolol 0.5% (Extravan, Alcon Laboratories) administered once daily is safe, well-tolerated, and offers better IOP lowering than monotherapy using either of its components, said Howard S. Barnebey, MD.

Uppsala, Sweden—Adjunctive latanoprost (Xalatan, Pfizer) therapy for open-angle glaucoma is safe and effective, based on the results of a 5-year assessment of the drug. The mean decrease in IOP was 25% of the baseline IOP and this was sustained without any treatment change in 70% of eyes.

New Orleans—Patient adherence to prostaglandin analogue or prostamide therapy for glaucoma is high but not perfect. There are still opportunities to improve adherence to therapy with these drugs, according to Jacob Wilensky, MD.

New Orleans—The ExPRESS miniature glaucoma shunt (Optonol Ltd., Neve Ilan, Israel; marketed by CIBA Vision, Duluth, GA), originally intended to be placed through the limbus and under a conjunctival flap, produced significant IOP lowering yet an unacceptable high rate of complications. So researchers are now investigating placement of the device under a scleral flap, according to Marlene R. Moster, MD.

New Orleans—Bleb needling may be a good approach for early bleb failure if medication, digital massage, and suture lysis or removal are not effective. In the case of late bleb failure, YAG laser lysis of the sclerotomy, bleb needling, and bleb revision are favored, according to glaucoma specialist Jon M. Ruderman, MD.