Take-home message: The rate of postoperative cystoid macular edema was lower in a recent study of nearly 1,000 cataract surgery patients at two sites using intravitreal transzonular antibiotic and steroid prophylaxis than in previous studies with topical administration.
Sparta, NJ â The incidence of postoperative cystoid macular edema (CME) was very low following intravitreal transzonular injection of triamcinolone-moxifloxacin-vancomycin (Tri-Moxi-Vanc, Imprimis) or triamcinolone-moxifloxacin (Tri-Moxi, Imprimis) without the use of preoperative topical nonsteroidal anti-inflammatory drugs (NSAIDs).
In addition, there was no difference in CME incidence between the two intravitreal formulations used in the study, conducted by two private practice surgeons in different states.
However, there was a slight increase in the incidence of CME among patients with known risk factors.
The overall incidence of CME with intravitreal injection of either formulation used in the Dropless therapy was 1.2%, lower than in previous studies of topical administration, said Jeffrey Liegner, MD, co-author of the study.